Barbiturates can induce hepatic microsomal enzymes resulting in enhanced metabolism and lessened anticoagulant reaction of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); sufferers stabilized on anticoagulant therapy could call for dosage adjustments if barbiturates are added to or withdrawn from their dosage regime
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If opioid use is required for a chronic time period in Expecting Ladies, suggest the client of the risk of neonatal opioid withdrawal syndrome and be sure that appropriate procedure will likely be readily available.OxyContin tablets need to be swallowed full, and not broken, chewed or crushed. The administration of damaged, chewed, or crushed OxyCo
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